Characterization of a New Monocrotaline Rat Model to Study Chronic Neonatal Pulmonary Hypertension

Flore Lesage; Yupu Deng; Laurent Renesme; Fanny Sauvestre; Nadya Ben Fadel; Shumei Zhong; Arul Vadivel; Robert P Jankov; Duncan J Stewart; Bernard Thébaud

doi:10.1165/rcmb.2021-0039LE

Characterization of a New Monocrotaline Rat Model to Study Chronic Neonatal Pulmonary Hypertension

Am J Respir Cell Mol Biol. 2021 Sep;65(3):331-334. doi: 10.1165/rcmb.2021-0039LE.

Authors

Flore Lesage^{1

2}, Yupu Deng^{1

2}, Laurent Renesme^{1

2}, Fanny Sauvestre³, Nadya Ben Fadel⁴, Shumei Zhong^{1

2}, Arul Vadivel^{1

2}, Robert P Jankov^{2

4

5}, Duncan J Stewart^{1

2}, Bernard Thébaud^{1

2

4

5}

Affiliations

¹ Ottawa Hospital Research Institute Ottawa, Ontario, Canada.
² University of Ottawa Ottawa, Ontario, Canada.
³ Pellegrin Hospital Bordeaux, France.
⁴ Children's Hospital of Eastern Ontario Ottawa, Ontario, Canada.
⁵ Children's Hospital of Eastern Ontario Research Institute Ottawa, Ontario, Canada.

PMID: 34468292
DOI: 10.1165/rcmb.2021-0039LE

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Animals, Newborn
Chronic Disease
Disease Models, Animal*
Humans
Hypertension, Pulmonary* / chemically induced
Hypertension, Pulmonary* / metabolism
Hypertension, Pulmonary* / pathology
Monocrotaline / toxicity*
Rats

Substances

Monocrotaline