Diversity in chromosome numbers promotes resistance to chemotherapeutics

Dev Cell. 2021 Sep 13;56(17):2399-2400. doi: 10.1016/j.devcel.2021.08.017. Epub 2021 Sep 13.

Abstract

In this issue of Developmental Cell, papers from Ippolito et al. and from Lukow et al. show that increasing the range of aneuploidy states in cells increases their chance of developing resistance when they are subjected to chemotherapy.

Publication types

  • Comment

MeSH terms

  • Aneuploidy*
  • Chromosomes*
  • Humans