Left behind: The potential impact of CFTR modulators on racial and ethnic disparities in cystic fibrosis

Abstract

The advent of CFTR modulators, a genomic specific medication, revolutionized the treatment of CF for many patients. However, given that these therapeutics were only developed for specific CFTR mutations, not all people with CF have access to such disease-modifying drugs. Racial and ethnic minority groups are less likely to have CFTR mutations that are approved for CFTR modulators. This exclusion has the potential to widen existing health disparities.

Keywords: CFTR modulators; Cystic fibrosis; Ethnicity; Race.