Nanofat and Platelet-Rich Plasma injections used in a case of severe acne scars

J Stomatol Oral Maxillofac Surg. 2022 Oct;123(5):572-575. doi: 10.1016/j.jormas.2022.04.018. Epub 2022 Apr 26.

Abstract

Background: Acne is a common chronic inflammatory disease, which can result in permanent scarring. Different types of treatments have been used in order to treat acne scars. However, esthetic results have proved variable. Furthermore, none of these treatments has had an impact on the underlying inflammatory process.

Objective: The main purpose of this case-report is to suggest a new potential therapy for acne scar management combining esthetic filling with an anti-inflammatory and a regenerative action.

Methods: A Platelet rich plasma (PRP) and Nanofat mixture was injected into the pathological dermis in order to treat and fill severe acne scars.

Results: After a one- year follow-up, skin elasticity had improved, scar reduction and a reversal of the inflammation process had been observed.

Conclusions: PRP and Nanofat could represent a new and promising therapeutic approach in the treatment of the inflammatory scarring process in severe acne.

Keywords: Acne scars; Adipose stem cells; Nanofat; Platelet rich plasma; Stromal vascular.

Publication types

  • Case Reports

MeSH terms

  • Acne Vulgaris* / complications
  • Acne Vulgaris* / pathology
  • Acne Vulgaris* / therapy
  • Cicatrix / etiology
  • Cicatrix / pathology
  • Cicatrix / therapy
  • Combined Modality Therapy
  • Humans
  • Platelet-Rich Plasma*
  • Skin
  • Treatment Outcome