Objective:To investigate the effect of transoral endoscopic thyroid surgery in the central lymph node dissection of thyroid cancer. Methods:Twenty patients underwent endoscopic thyroidectomy via oral vestibular approach （TOETVA group） and 20 gender and age matched patients underwent conventional open thyroidectomy were selected in this study. The clinical data, number of lymph node dissection and postoperative complications of the two groups were collected and analyzed. SPSS 24.0 statistical software was used for data analysis. Results:There was no significant differences in age, BMI, tumor size or the number of Hashimoto's thyroiditis patients between the TOETVA group and the open group（P>0.05）. The operation time（[117.30±10.54]min） and postoperative drainage volume（[146.05±30.66]mL） in the TOETVA group were significantly higher than those in the open group（[59.05±6.40]min, [77.90±22.18]mL）, P<0.001. The pain in the open group 24 h after surgery was more severe than that in the TOETVA group（P<0.05）. The total number of central lymph nodes, the number of pre-laryngeal lymph nodes and the number of pre-tracheal lymph nodes cleared by the two groups were similar, and the number of final positive lymph nodes had no significant difference. However, the number of paratracheal lymph nodes removed in the TOETVA group was more（7.8±4.2） nodes than that in the open group（6.4±3.9） nodes, P<0.05. There was no significant difference in postoperative complications between the two groups. The scores of cosmetic evaluation and rating of cicatrices in the TOETVA group six months after surgery were（0.77±0.58） significantly lower than those in the open group（4.30±1.54）, P<0.001. Conclusion:In central lymph node dissection, the efficiency of TOETVA is similar to that of traditional open thyroid surgery. For special anatomical regions, endoscopic surgery is more efficient. At the same time, TOETVA does not increase the incidence of related complications, and has good cosmetic effect.
目的：探讨经口腔前庭入路腔镜手术在甲状腺癌中央区淋巴结清扫中的效果。 方法：根据纳入标准，确定行经口腔前庭入路腔镜甲状腺手术（TOETVA）患者20例（TOETVA组），在同样标准下，按照性别、年龄匹配行传统开放甲状腺手术患者20例（开放组），收集分析两组患者的临床资料、手术相关数据、淋巴结清扫数及术后并发症。采用SPSS 24.0统计软件进行数据分析。 结果：TOETVA组和开放组患者的年龄、BMI、肿瘤大小及桥本甲状腺炎患者数的差异均无统计学意义（P>0.05）；TOETVA组的手术时间[（117.30±10.54） min]及术后引流量[（146.05±30.66） mL]显著高于开放组[（59.05±6.40） min，（77.90±22.18） mL]，均P<0.001。开放组患者术后24 h疼痛较TOETVA组更强烈（P<0.05）。两组清扫的总中央组淋巴结数目、喉前淋巴结数目及气管前淋巴结数目相似，最终阳性淋巴结数目无明显差异；但TOETVA组清扫的气管旁淋巴结数目[（7.8±4.2）枚]较开放组[（6.4±3.9）枚]更多，P<0.05。两组术后并发症的差异无统计学意义。TOETVA组患者术后6个月瘢痕美容评估与评级得分（0.77±0.58）明显低于开放组（4.30±1.54），P<0.001。 结论：在中央区淋巴结清扫中，TOETVA与传统开放甲状腺手术的清扫效率相似，对于特殊解剖区域，腔镜手术效率更高；同时TOETVA不增加相关并发症发生率，且美容效果好。.
Keywords: central lymph node dissection; thyroid neoplasms; transoral vestibular approach.
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