Background: Neurofibromatosis syndromes such as neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis often result in painful symptoms related to tumor burden.
Observations: Painful symptoms classically associated with common points of peripheral nerve entrapment, such as common peroneal neuropathy at the fibular tunnel, may present in patients both with and without focal tumor involvement.
Lessons: Surgical decompression at the point of entrapment, with or without resection of tumor, may provide symptomatic relief. Examples of surgical decompression at the point of entrapment, both with and without resection of tumor, are presented.
Keywords: MRI = magnetic resonance imaging; VAS = visual analog scale; common peroneal nerve; double-crush syndrome; peripheral nerve entrapment; peroneal tunnel syndrome; schwannomatosis.
© 2021 The authors.