Recurrent vulvovaginal candidiasis with Candida glabrata - a management conundrum

Int J STD AIDS. 2022 Sep;33(10):939-942. doi: 10.1177/09564624221118739. Epub 2022 Aug 13.

Abstract

High rates of azole-resistance and limited availability of pharmacological agents within the UK can make recurrent vulvovaginal candidiasis (RVVC) with Candida glabrata a challenging infection to treat. In this report, we describe our experience in managing C. glabrata RVVC and present the case of a patient with poor response to therapy and a protracted treatment course, spanning almost 4 years. We also highlight the need for evidence-based management protocols that consider the national availability of alternative treatments.

Keywords: Antifungal; treatment; women.

Publication types

  • Case Reports

MeSH terms

  • Azoles / therapeutic use
  • Candida glabrata*
  • Candidiasis, Vulvovaginal* / diagnosis
  • Candidiasis, Vulvovaginal* / drug therapy
  • Female
  • Humans
  • Recurrence

Substances

  • Azoles