Diphtheritic myocarditis: a case report, with toxinmediated complications and multi-organ involvement

Cardiovasc J Afr. 2023;34(2):117-120. doi: 10.5830/CVJA-2022-032. Epub 2022 Sep 5.

Abstract

The re-emergence of diphtheria in South Africa in recent years warns of incomplete vaccination coverage. Recent outbreaks have been associated with a high mortality rate, due to late presentation, limited access to antitoxin and the occurrence of serious systemic complications. Death due to diphtheria is most commonly associated with diphtheritic myocarditis, which presents with heart failure, cardiogenic shock and conduction abnormalities. This case highlights the key clinical features and systemic complications, and examines the reasons for the return of diphtheria in our community.

Keywords: diphtheria; heart block; myocarditis.

Publication types

  • Case Reports

MeSH terms

  • Diphtheria* / complications
  • Electrocardiography
  • Heart Failure* / complications
  • Humans
  • Myocarditis* / diagnosis
  • Myocarditis* / etiology
  • Myocarditis* / therapy
  • South Africa