Pulmonary Vascular Sequelae of Palliated Single Ventricle Circulation: Arteriovenous Malformations and Aortopulmonary Collaterals

Andrew D Spearman; Salil Ginde

doi:10.3390/jcdd9090309

Pulmonary Vascular Sequelae of Palliated Single Ventricle Circulation: Arteriovenous Malformations and Aortopulmonary Collaterals

J Cardiovasc Dev Dis. 2022 Sep 17;9(9):309. doi: 10.3390/jcdd9090309.

Authors

Andrew D Spearman^{1

2}, Salil Ginde^{1

2

3}

Affiliations

¹ Department of Pediatrics, Division of Cardiology, Medical College of Wisconsin, Children's Wisconsin, Herma Heart Institute, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
² Cardiovascular Center, Medical College of Wisconsin, 8701 West Watertown Plank Road, Milwaukee, WI 53226, USA.
³ Department of Medicine, Division of Cardiology, Medical College of Wisconsin, 8701 West Watertown Plank, Milwaukee, WI 53226, USA.

Abstract

Children and adults with single ventricle congenital heart disease (CHD) develop many sequelae during staged surgical palliation. Universal pulmonary vascular sequelae in this patient population include two inter-related but distinct complications: pulmonary arteriovenous malformations (PAVMs) and aortopulmonary collaterals (APCs). This review highlights what is known and unknown about these vascular sequelae focusing on diagnostic testing, pathophysiology, and areas in need of further research.

Keywords: Fontan; Glenn; aortopulmonary collaterals; congenital heart disease; hepatic factor; pulmonary arteriovenous malformations; single ventricle.

Publication types

Review

Abstract

Publication types

Grants and funding