Cytotoxic Chemotherapy in Advanced Pancreatic Cancer

Hematol Oncol Clin North Am. 2022 Oct;36(5):1011-1018. doi: 10.1016/j.hoc.2022.07.006. Epub 2022 Sep 22.

Abstract

Advanced pancreatic cancer remains one of the deadliest malignancies in 2022. Although there has been significant progress in treatment options with improved outcomes in many cancers, this growth has been slow in pancreatic cancer. This article examines specific components of approved first- and second-line therapies for advanced pancreatic cancer treatment and their effectiveness and concludes with a brief exploration of future directions for targeted therapies.

Keywords: Advanced pancreatic cancer treatment; Chemotherapy for pancreatic cancer; Metastatic pancreatic cancer.

Publication types

  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Humans
  • Pancreatic Neoplasms* / drug therapy
  • Pancreatic Neoplasms* / pathology