Rationale and Design for the COCKTAIL Trial: A Single-center, Randomized, Double-blind, Sham-controlled Study Combining Shockwave Therapy and Platelet-rich Plasma for Erectile Dysfunction

Russell G Saltzman; Manuel L Molina; Braian R Ledesma; Emad Ibrahim; Thomas A Masterson; Ranjith Ramasamy

doi:10.1016/j.euf.2022.09.015

Rationale and Design for the COCKTAIL Trial: A Single-center, Randomized, Double-blind, Sham-controlled Study Combining Shockwave Therapy and Platelet-rich Plasma for Erectile Dysfunction

Eur Urol Focus. 2023 Jan;9(1):8-10. doi: 10.1016/j.euf.2022.09.015. Epub 2022 Oct 22.

Authors

Russell G Saltzman¹, Manuel L Molina¹, Braian R Ledesma¹, Emad Ibrahim¹, Thomas A Masterson¹, Ranjith Ramasamy²

Affiliations

¹ Desai Sethi Urology Institute, Miller School of Medicine, University of Miami, Miami, FL, USA.
² Desai Sethi Urology Institute, Miller School of Medicine, University of Miami, Miami, FL, USA. Electronic address: ramasamy@miami.edu.

Abstract

Restorative therapies are a promising option for the treatment of erectile dysfunction. Several studies have assessed platelet-rich plasma and shockwave therapy alone. However, COCKTAIL is the first study to evaluate the synergistic effects of these two therapies in combination.

Trial registration: ClinicalTrials.gov NCT05048667.

Publication types

Randomized Controlled Trial
Research Support, N.I.H., Extramural

MeSH terms

Erectile Dysfunction* / therapy
Extracorporeal Shockwave Therapy*
High-Energy Shock Waves*
Humans
Male
Penile Erection
Platelet-Rich Plasma*

Associated data

ClinicalTrials.gov/NCT05048667

Grants and funding

R01 DK130991/DK/NIDDK NIH HHS/United States