Case report: rTMS in combination with aripiprazole and sodium valproate for the maintenance treatment of rapid cycling bipolar disorder

Siyi Tao; Bing Chen; Xiaofang Xu; Shaohua Hu; Jing Lu

doi:10.3389/fpsyt.2023.1070046

Case report: rTMS in combination with aripiprazole and sodium valproate for the maintenance treatment of rapid cycling bipolar disorder

Front Psychiatry. 2023 Mar 16:14:1070046. doi: 10.3389/fpsyt.2023.1070046. eCollection 2023.

Authors

Siyi Tao^{1

2}, Bing Chen¹, Xiaofang Xu¹, Shaohua Hu^{1

3}, Jing Lu^{1

3}

Affiliations

¹ Department of Psychiatry, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
² Department of Nursing, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
³ The Key Laboratory of Mental Disorder Management in Zhejiang Province, Hangzhou, China.

Abstract

As a safe neuromodulation therapy, rTMS is applied to treat a variety of psychiatric and neurological disorders. Additionally, both aripiprazole and sodium valproate are effective in the treatment of rapid cycling bipolar disorder. This case reports a female patient with a 17-year history of bipolar disorder who developed rapid-circulation bipolar disorder 5 years prior to presentation. After combined treatment with rTMS, aripiprazole, and sodium valproate, the patient's mood remained stable and she was able to live and work normally.

Keywords: aripiprazole; bipolar disorder; rapid cycling; repetitive transcranial magnetic stimulation; sodium valproate.

Publication types

Case Reports