Ophthalmology at the Forefront of Big Data Integration in Medicine: Insights from the IRIS Registry Database

Austen N Knapp; Theodore Leng; Ehsan Rahimy

doi:10.59249/VUPM2510

Ophthalmology at the Forefront of Big Data Integration in Medicine: Insights from the IRIS Registry Database

Yale J Biol Med. 2023 Sep 29;96(3):421-426. doi: 10.59249/VUPM2510. eCollection 2023 Sep.

Authors

Austen N Knapp¹, Theodore Leng¹, Ehsan Rahimy^{1

2}

Affiliations

¹ Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
² Department of Ophthalmology, Palo Alto Medical Foundation, Palo Alto, CA, USA.

Abstract

Ophthalmology stands at the vanguard of incorporating big data into medicine, as exemplified by the integration of The Intelligent Research in Sight (IRIS) Registry. This synergy cultivates patient-centered care, demonstrates real world efficacy and safety data for new therapies, and facilitates comprehensive population health insights. By evaluating the creation and utilization of the world's largest specialty clinical data registry, we underscore the transformative capacity of data-driven medical paradigms, current shortcomings, and future directions. We aim to provide a scaffold for other specialties to adopt big data integration into medicine.

Keywords: big data; clinical trials; iris registry; ophthalmology; real-world data.

Publication types

Review

MeSH terms

Big Data
Databases, Factual
Humans
Medicine*
Ophthalmology*
Registries