Diffuse peritoneal carcinomatosis and Sister Mary Joseph nodule in ovarian carcinoma - exquisite demonstration of the peritoneal reflections on [18F]FDG PET/CT

Nucl Med Rev Cent East Eur. 2023;26(0):153-155. doi: 10.5603/nmr.96954.

Abstract

A case involving a 64-year-old woman with ovarian carcinoma on maintenance therapy who underwent 18-fluorodeoxyglucose positron emission tomography with computed tomography ([18F]FDG PET/CT) restaging due to rapid cancer antigen 125 (Ca-125) rise. This revealed recurrent disease within the pelvis and large volume, peritoneal carcinomatosis including an avid umbilical deposit, consistent with the rarely seen Sister Mary Joseph nodule (SMJN). This case elegantly demonstrates not only the anatomy of the peritoneal surfaces through avid disease deposition but also highlights the sensitive depiction of disease burden in peritoneal carcinomatosis, including the detection of rare manifestations such as SMJN.

Keywords: FDG PET/CT; Sister Mary Joseph nodule; peritoneal carcinomatosis.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma*
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Middle Aged
  • Ovarian Neoplasms* / diagnostic imaging
  • Ovarian Neoplasms* / pathology
  • Peritoneal Neoplasms* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography / methods
  • Sister Mary Joseph's Nodule* / diagnostic imaging

Substances

  • Fluorodeoxyglucose F18