The role of the mineralocorticoid receptor in steroidinduced cytotoxicity in pediatric acute lymphoblastic leukemia

Annelienke M Van Hulst; Jordy C G Van der Zwet; Jessica G C A M Buijs-Gladdines; Willem K Smits; Marta Fiocco; Rob Pieters; Frank N Van Leeuwen; Marry M Van den Heuvel-Eibrink; Erica L T Van den Akker; Jules P P Meijerink

doi:10.3324/haematol.2023.282928

The role of the mineralocorticoid receptor in steroidinduced cytotoxicity in pediatric acute lymphoblastic leukemia

Haematologica. 2024 May 1;109(5):1551-1556. doi: 10.3324/haematol.2023.282928.

Affiliations

¹ Princess Maxima Center for Pediatric Oncology, Utrecht. a.vanhulst@prinsesmaximacentrum.nl.
² Princess Maxima Center for Pediatric Oncology, Utrecht.
³ Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands; Mathematical Institute, Leiden University, Leiden, The Netherlands; Department of Biomedical data Science, Medical Statistics, Leiden University Medical Centre.
⁴ Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands; Child Health, UMCU-Wilhelmina Children's Hospital, Utrecht. m.m.vandenheuvel-eibrink@prinsesmaximacentrum.nl.
⁵ Pediatric Endocrinology, Erasmus MC- Sophia Children's Hospital, Rotterdam.
⁶ Princess Maxima Center for Pediatric Oncology, Utrecht, The Netherlands; Presently working at Acerta-Pharma (AstraZeneca), Oss.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Child
Child, Preschool
Humans
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / pathology
Receptors, Mineralocorticoid* / metabolism

Substances

Receptors, Mineralocorticoid

Grants and funding

Funding: This study was sponsored by grants from the “Kinderen Kankervrij” Foundation, KiKa-219 (to JCGvdZ), KiKa-92 and KiKa-295 (to WKS), and KiKa-268 (to AMvH).