Weight Gain in Midlife Women

Curr Obes Rep. 2024 Jun;13(2):352-363. doi: 10.1007/s13679-024-00555-2. Epub 2024 Feb 28.

Abstract

Purpose of review: To summarize the evidence and clinical implications of weight and body composition changes during midlife in women and provide an overview of weight gain prevention and management in this population.

Recent findings: Aging-related changes such as decreased energy expenditure and physical activity are important culprits for weight gain in midlife women. The hormonal changes of menopause also influence body adiposity distribution and increase central adiposity. These body changes can have health consequences including the development of cardiometabolic diseases, osteoarthritis, cancer, worsening in cognition, mental health, and menopause symptoms. Midlife women experience changes related to aging, menopause, and lifestyle which favor weight gain. Clinical practice should focus on early counseling and anticipatory guidance on the importance of dietary changes and physical activity to attenuate this phenomenon. Future research should focus on the longitudinal relationship between weight trends in midlife and health consequences and mortality.

Keywords: Body composition; Lifestyle intervention; Metabolic rate; Midlife women; Weight gain.

Publication types

  • Review

MeSH terms

  • Adiposity
  • Aging* / physiology
  • Body Composition
  • Energy Metabolism
  • Exercise*
  • Female
  • Humans
  • Life Style
  • Menopause* / physiology
  • Middle Aged
  • Obesity
  • Weight Gain*