Abstract
Thirty-seven adult patients with acute lymphoblastic leukemia were treated with a protocol called HEAV'D including Adriamycin, Vincristine, L-Asparaginase, Cyclophosphamide and Dexamethasone. The complete remission rate was 70 per cent. The median duration of remission was more than 30 months. Patients with initial leukocyte count below 20 000/mmc experienced a longer remission (median not reached) than patients with a leukocyte count above 20 000/mmc (median 10 months).
MeSH terms
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Adolescent
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Asparaginase / administration & dosage
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Child
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Cyclophosphamide / administration & dosage
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Dexamethasone / administration & dosage
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Doxorubicin / administration & dosage
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Female
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Humans
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Leukemia, Lymphoid / drug therapy*
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Leukemia, Lymphoid / mortality
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Male
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Middle Aged
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Recurrence
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Time Factors
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Vincristine / administration & dosage
Substances
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Vincristine
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Dexamethasone
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Doxorubicin
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Cyclophosphamide
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Asparaginase