Precise timing of audiovisual stimulation conquers chemobrain

Trends Cancer. 2024 May;10(5):386-388. doi: 10.1016/j.trecan.2024.04.002. Epub 2024 Apr 21.

Abstract

In a recent study, Kim et al. utilized gamma entrainment using sensory stimuli (GENUS) to rescue cognitive impairment and glial dysregulation associated with cisplatin and methotrexate chemotherapy, specifically when applied both throughout and after chemotherapy administration. GENUS provides a time-dependent, non-invasive method for treating chemobrain, with broader implications for resolving neurodegenerative neuroinflammation.

Keywords: GENUS; audiovisual stimulation; chemobrain; chemotherapy; cognitive impairment; neuroinflammation.

MeSH terms

  • Acoustic Stimulation
  • Animals
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Cisplatin* / adverse effects
  • Cognitive Dysfunction / chemically induced
  • Humans
  • Methotrexate / adverse effects
  • Photic Stimulation
  • Time Factors