During March and April 2024, we studied dairy cattle specimens from a single farm in Texas, USA, using multiple molecular, cell culture, and next-generation sequencing pathogen detection techniques. Here, we report evidence that highly pathogenic avian influenza A(H5N1) virus strains of clade 2.3.4.4b were the sole cause of this epizootic.
Keywords: H5N1; Texas; United States; cattle; epidemiology; highly pathogenic avian influenza virus; influenza; influenza A virus; viruses.