AlphaMissense versus laboratory-based pathogenicity prediction of 13 novel missense CPA1 variants from pancreatitis cases

Affiliations

• ¹ Department of Surgery, University of California Los Angeles, Los Angeles, California, USA.
• ² Department of Pediatric Gastroenterology and Hepatology, Cliniques universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
• ³ Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.
• ⁴ Paediatric Nutritional Medicine, Else Kröner-Fresenius Zentrum für Ernährungsmedizin (EKFZ), Technische Universität München (TUM), Freising, Germany.
• ⁵ Ariel Precision Medicine, Pittsburgh, Pennsylvania, USA.
• ⁶ Univ Brest, Inserm, EFS, UMR 1078, GGB, F-29200, Brest, France.
• ⁷ Center for Gastroenterology, Department of Medicine, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
• ⁸ Hungarian Centre of Excellence for Molecular Medicine, Translational Pancreatology Research Group, Albert Szent-Györgyi Medical School, University of Szeged, Szeged, Hungary.
• ⁹ Department of Surgery, Boston University, Boston, Massachusetts, USA.
• ¹⁰ Stead Family Department of Pediatrics and Department of Radiation Oncology, University of Iowa, Iowa City, Iowa, USA.
• ¹¹ Department of Surgery, University of California Los Angeles, Los Angeles, California, USA msahintoth@mednet.ucla.edu.