Towards integrated malaria molecular surveillance in Africa

Nsa Dada; Victoria J Simpson; Lucas N Amenga-Etego; Eniyou Oriero; Olivo Miotto; Mili Estee Torok; Elijah O Juma; Nana Aba Williams; Shavanthi Rajatileka; Cristina V Ariani; Jaishree Raman; Deus S Ishengoma

doi:10.1016/j.pt.2024.09.005

Towards integrated malaria molecular surveillance in Africa

Trends Parasitol. 2024 Nov;40(11):964-969. doi: 10.1016/j.pt.2024.09.005. Epub 2024 Oct 29.

Authors

Affiliations

¹ School of Life Sciences, Arizona State University, Tempe, AZ, USA; Center for Fundamental and Applied Microbiomics, The Biodesign Institute, Arizona State University, Tempe, AZ, USA. Electronic address: Nsa.Dada@asu.edu.
² Genomic Surveillance Unit, Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK.
³ West African Centre for Cell Biology of infectious Pathogens, University of Ghana, Accra, Ghana.
⁴ The Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine, Fajara, Gambia.
⁵ Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
⁶ The Bill & Melinda Gates Foundation, London, UK.
⁷ The Pan-African Mosquito Control Association (PAMCA), KEMRI HQ, Nairobi, Kenya.
⁸ MESA, The Malaria Knowledge Hub, Barcelona Institute for Global Health (ISGlobal), Hospital Clinic-Universitat de Barcelona, Barcelona, Spain.
⁹ Centre for Emerging Zoonotic and Parasitic Diseases, National Institute for Communicable Diseases, Johannesburg, South Africa; Wits Research Institute for Malaria, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; UP Institute for Sustainable Malaria Control, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
¹⁰ National Institute for Medical Research, Dar es Salaam, Tanzania; Harvard T.H. Chan School of Public Health, Boston, MA, USA; Kampala International University in Tanzania, Dar es Salaam, Tanzania. Electronic address: deusdedith.ishengoma@nimr.or.tz.

Abstract

Integrated malaria molecular surveillance (iMMS) systems are essential for Africa's expanding malaria genomics initiatives. Here we highlight a few initiatives and demonstrate how iMMS can support evidence-based decisions and policies for National Malaria Programs and other malaria control stakeholders. We conclude with key considerations for advancing these malaria genomics initiatives towards sustainable iMMS.

Keywords: genomic surveillance; genomics; malaria; molecular surveillance; regional hubs.

Publication types

Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Africa / epidemiology
Epidemiological Monitoring
Genomics
Humans
Malaria* / epidemiology
Malaria* / prevention & control
Population Surveillance

Abstract

Publication types

MeSH terms

Grants and funding