Respiratory Outcomes of Infants Born Extremely Preterm in the Necrotizing Enterocolitis Surgery Trial

J Pediatr. 2025 Feb:277:114391. doi: 10.1016/j.jpeds.2024.114391. Epub 2024 Nov 8.

Abstract

The multicenter Necrotizing Enterocolitis Surgery Trial compared initial peritoneal drainage with laparotomy among infants with extremely low birth weight and surgical necrotizing enterocolitis or intestinal perforation. In this post hoc analysis of trial data, initial drainage was associated with adverse respiratory outcomes, both in hospital and through 2 years corrected age.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Drainage* / adverse effects
  • Enterocolitis, Necrotizing* / surgery
  • Female
  • Humans
  • Infant
  • Infant, Extremely Premature*
  • Infant, Newborn
  • Infant, Premature, Diseases* / surgery
  • Intestinal Perforation* / surgery
  • Laparotomy
  • Male
  • Treatment Outcome