The epigenetic trajectory of type 1 regulatory T cells

David P Turicek; Xiaoxiao Wan

doi:10.7554/eLife.104239

The epigenetic trajectory of type 1 regulatory T cells

Elife. 2024 Nov 14:13:e104239. doi: 10.7554/eLife.104239.

Authors

David P Turicek^{1

2}, Xiaoxiao Wan^{1

2}

Affiliations

¹ Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, United States.
² The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St Louis, United States.

Abstract

The epigenome of T follicular helper cells prepares them for conversion into type 1 regulatory T cells.

Keywords: T follicular helper cells; epigenetics; immunology; immunoregulation; inflammation; mouse; nanomedicine; transdifferentiation; type 1 regulatory T cells.

MeSH terms

Animals
Epigenesis, Genetic*
Humans
T-Lymphocytes, Regulatory* / immunology