Ancestral Differences in Anticancer Treatment Efficacy and Their Underlying Genomic and Molecular Alterations

Cancer Discov. 2025 Mar 3;15(3):511-529. doi: 10.1158/2159-8290.CD-24-0827.

Abstract

Our study charts a global landscape of ancestry-associated differences in therapeutic efficacy, highlighting the importance of considering ancestry in anticancer therapies.

MeSH terms

  • Antineoplastic Agents* / therapeutic use
  • Genomics / methods
  • Humans
  • Neoplasms* / drug therapy
  • Neoplasms* / genetics
  • Treatment Outcome

Substances

  • Antineoplastic Agents