A Novel HLA-C Allele, HLA-C*12:419, Was Identified by Next-Generation Sequencing in a Chinese Individual

HLA. 2024 Dec;104(6):e15785. doi: 10.1111/tan.15785.

Abstract

HLA-C*12:419 has a single nucleotide substitution at position 445 G>T when compared to the C*12:02:02:25 allele.

Keywords: HLA‐C*12:419; HLA; next‐generation sequencing; novel allele.

MeSH terms

  • Alleles
  • East Asian People / genetics
  • Exons*
  • HLA-C Antigens* / genetics
  • High-Throughput Nucleotide Sequencing / methods
  • Histocompatibility Testing / methods
  • Humans
  • Polymorphism, Single Nucleotide
  • Sequence Analysis, DNA / methods

Substances

  • HLA-C Antigens
  • HLA-C*12 antigen