Heterologous biosynthesis of saponin adjuvants from Quillaja saponaria: A symbolic achievement in metabolic engineering

Acta Pharm Sin B. 2024 Dec;14(12):5518-5520. doi: 10.1016/j.apsb.2024.09.013. Epub 2024 Sep 19.

Weiqiang Chen^{1

2}, Zhichao Xu³, Wei Sun^{1

2}

¹ State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
² Key Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
³ College of Life Science, Northeast Forestry University, Harbin 150040, China.

No abstract available

Keywords: Heterologous biosynthesis; Plant natural products (PNPs); QS-21; QS-7.