Chapter 11: Treatment modalities

Grégory Baud; Stéphanie Espiard; Camille Buffet; Adrien Ben Hamou; Héloise Henry; Nunza Cinzia Paladino; Frédéric Sebag; Bernard Goichot

doi:10.1016/j.ando.2025.101700

Chapter 11: Treatment modalities

Ann Endocrinol (Paris). 2025 Feb;86(1):101700. doi: 10.1016/j.ando.2025.101700. Epub 2025 Jan 14.

Authors

Grégory Baud¹, Stéphanie Espiard², Camille Buffet³, Adrien Ben Hamou⁴, Héloise Henry⁵, Nunza Cinzia Paladino⁶, Frédéric Sebag⁶, Bernard Goichot⁷

Affiliations

¹ Department of General and Endocrine Surgery, CHU de Lille, 59000 Lille, France. Electronic address: gregory.baud@chru-lille.fr.
² Endocrinology, Diabetology, Metabolism & Nutrition, CHU de Lille, 59000 Lille, France.
³ Thyroid and Endocrine Tumors Department, Pitié-Salpêtrière Hospital, Thyroid Tumors Clinical Research Group, Sorbonne University, Cancer Institute, Inserm U1146, CNRS UMR, 7371 Paris, France.
⁴ Thyroid and Endocrine Tumors Department, Institute of Endocrinology, Pitié-Salpêtrière Hospital AP-HP, Sorbonne University, 75013 Paris, France; American Hospital of Paris, Thyroid Unit, 92200 Neuilly-sur-Seine, France.
⁵ Université de Lille, CHU de Lille, ULR 7365-GRITA-Groupe de Recherche sur les Formes Injectables et les Technologies Associées, F-59000 Lille, France.
⁶ Department of General Endocrine and Metabolic Surgery, Conception University Hospital, Aix-Marseille University, 147, boulevard Baille, 13005 Marseille, France.
⁷ Internal Medicine, Diabetes and Metabolic Disorders, University Hospitals of Strasbourg, Strasbourg University, Strasbourg, France.

PMID: 39818297
DOI: 10.1016/j.ando.2025.101700

Abstract

Treatment modalities for primary hyperparathyroidism must take account of the expected benefits and risks of each treatment envisaged, before choosing the definitive option to be proposed to the patient. In this section, a Foreword puts in perspective the difficulties involved in choosing the criteria for a particular treatment method. Treatments are then considered one after the other: surgery, local destruction and medical management. This section does not consider therapeutic indications, which are dealt with in a section 9.

Keywords: Medical treatment; Parathyroidectomy; Primary hyperparathyroidism; Surgical approaches; Thermoablation.

Publication types

Practice Guideline

MeSH terms

Combined Modality Therapy
Endocrinology* / methods
Endocrinology* / organization & administration
Endocrinology* / standards
Humans
Hyperparathyroidism, Primary* / surgery
Hyperparathyroidism, Primary* / therapy
Parathyroidectomy / methods