Iliofemoral Acute Deep Venous Thrombosis, Chronic Deep Venous Thrombosis, and May-Thurner Syndrome

Interv Cardiol Clin. 2025 Apr;14(2):297-310. doi: 10.1016/j.iccl.2024.11.014. Epub 2025 Jan 24.

Abstract

Acute iliofemoral deep vein thrombosis (DVT) is associated with higher rates of severe chronic symptoms and complications, and in rare cases with acute limb ischemia. Early detection is a key to provide prompt treatment, including endovascular intervention, in selected patients. When iliofemoral DVT is related to external compression of the left iliac vein by the right common iliac artery is termed May-Thurner syndrome. Approximately, 20% to 50% of patients with chronic DVT will develop post-thrombotic syndrome, a collection of symptoms including lower extremity edema, skin changes, vein dilation, pain, fatigue, and ulcer formation.

Keywords: And may-thurner syndrome; Chronic deep venous thrombosis; Iliac vein stenting; Iliofemoral acute deep venous thrombosis; Venous thrombectomy.

Publication types

  • Review

MeSH terms

  • Acute Disease
  • Chronic Disease
  • Endovascular Procedures / methods
  • Femoral Vein* / diagnostic imaging
  • Humans
  • Iliac Vein* / diagnostic imaging
  • May-Thurner Syndrome* / diagnosis
  • May-Thurner Syndrome* / therapy
  • Venous Thrombosis* / complications
  • Venous Thrombosis* / diagnosis
  • Venous Thrombosis* / therapy