We propose a methodology to measure the cosmological spatial curvature by employing the deviation from statistical isotropy due to the Alcock-Paczyński effect of large scale galaxy clustering. This approach has a higher degree of model independence than most other proposed methods, being independent of the calibration of standard candles, rulers, or clocks, of the power spectrum shape (and thus also of the prerecombination physics), of the galaxy bias, of the theory of gravity, of the dark energy model, and of the background cosmology in general. We find that a combined Dark Energy Spectroscopic Instrument-Euclid galaxy survey can achieve ΔΩ_{k0}=0.057 at 1σ C.L. in the redshift range z<2 by combining power-spectrum and bispectrum measurements.