Baicalin: an active natural product with potential medicinal values

J Asian Nat Prod Res. 2025 Apr 3:1-25. doi: 10.1080/10286020.2025.2482054. Online ahead of print.

Abstract

Baicalin, a flavonoid derived from the dicotyledonous plant Scutellaria baicalensis Georgi (SBG), is applied to treat various -disorders due to its various pharmacological effects such as anti-inflammatory, antiviral, antibacterial, liver-protecting, lipid-lowering, and neuroprotection. However, baicalin's limited solubility hampers absorption. This article reviews baicalin's pharmacological properties, including pharmacokinetics, cytotoxicity, drug interactions, and therapeutic potential, especially for cardiovascular diseases, obesity, and liver-lipid disorders, aiming to promote its development in medicine, dairy and livestock feed, nutritional health products and cosmetics for humans and other fields.

Keywords: Baicalin; bioavailability; cytotoxicity; pharmacological function; pharmacological properties.

Publication types

  • Review