Extrarenal Uptake of 99mTc-DMSA in Uterine Leiomyoma: From Misdiagnosis to Clarity With SPECT/CT Imaging

Clin Nucl Med. 2025 May 1;50(5):e317-e319. doi: 10.1097/RLU.0000000000005721. Epub 2025 Apr 7.

Abstract

We present a DMSA renal scan finding in a 42-year-old woman with new flank pain. Ultrasonography revealed hydronephrosis and renal stones. A 99mTc-DMSA renal scan showed global cortical loss and multiple cortical defects in the left kidney, with an incidental large zone of uptake in the abdominopelvic region initially suspected as bladder. SPECT/CT imaging clarified this as a large leiomyoma which is proved in permanent pathology. This case highlights the importance of advanced imaging to distinguish physiological organs from tumoral masses and avoid misdiagnosis.

Keywords: SPECT CT/CT; large leiomyoma; renal scan; uterine uptake.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biological Transport
  • Diagnostic Errors*
  • Female
  • Humans
  • Leiomyoma* / diagnostic imaging
  • Leiomyoma* / metabolism
  • Single Photon Emission Computed Tomography Computed Tomography*
  • Technetium Tc 99m Dimercaptosuccinic Acid* / metabolism
  • Uterine Neoplasms* / diagnostic imaging
  • Uterine Neoplasms* / metabolism

Substances

  • Technetium Tc 99m Dimercaptosuccinic Acid