Key advances in cardiac computed tomography: A review of the most relevant studies published in 2024 on coronary and structural heart disease

J Cardiovasc Comput Tomogr. 2025 May-Jun;19(3):291-298. doi: 10.1016/j.jcct.2025.04.008. Epub 2025 Apr 22.

Abstract

This review highlights the most relevant and influential studies on coronary and structural cardiac computed tomography published in 2024. The clinical utility of coronary CT angiography (CCTA) continues to expand, supported by advancements in quantitative plaque analysis, functional assessment through FFR-CT, and the integration of artificial intelligence (AI). Photon-counting CT has emerged as a promising technology for improving image quality and diagnostic accuracy. In structural heart disease, CCT has become an indispensable tool for procedural planning and risk stratification across multiple valvular interventions. Moreover, CT-derived extracellular volume (CT-ECV) and AI-based assessment of myocardial mass and epicardial adipose tissue are gaining traction as novel prognostic biomarkers. These developments reflect the growing adoption of CCT in both clinical practice and cardiovascular research, underscoring its role as a cornerstone modality in modern cardiology.

Keywords: Artificial intelligence; Cardiac computed tomography; Coronary artery disease; Quantitative plaque analysis; Structural heart disease.

Publication types

  • Review

MeSH terms

  • Computed Tomography Angiography* / trends
  • Coronary Angiography* / trends
  • Coronary Artery Disease* / diagnostic imaging
  • Coronary Artery Disease* / physiopathology
  • Coronary Artery Disease* / therapy
  • Coronary Vessels* / diagnostic imaging
  • Coronary Vessels* / physiopathology
  • Heart Diseases* / diagnostic imaging
  • Heart Diseases* / physiopathology
  • Heart Diseases* / therapy
  • Humans
  • Predictive Value of Tests
  • Prognosis
  • Reproducibility of Results