[Genetics in fetal medicine]

Ugeskr Laeger. 2025 Apr 28;187(18):V12240853. doi: 10.61409/V12240853.
[Article in Danish]

Abstract

The Danish prenatal program and genetic testing provide pregnant couples with the opportunity to learn about serious and potentially life-threatening fetal conditions. While invasive diagnostic methods remain the gold standard, advances in non-invasive technologies are emerging as valuable alternatives but they still have reduced resolution. Whole genome sequencing offers much increased resolution but raises challenges related to costs, uncertain findings, and secondary results. Counselling and multidisciplinary collaboration are critical to supporting couples navigating these complex decisions.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Denmark
  • Female
  • Fetal Diseases* / diagnosis
  • Fetal Diseases* / genetics
  • Genetic Counseling
  • Genetic Testing* / methods
  • Humans
  • Pregnancy
  • Prenatal Diagnosis* / methods
  • Whole Genome Sequencing