Carvedilol as Single Therapy for Heart Failure With Improved Ejection Fraction: A Randomized Clinical Trial (CATHEDRAL-HF)

JACC Heart Fail. 2025 Jun;13(6):1041-1044. doi: 10.1016/j.jchf.2025.02.022. Epub 2025 May 14.

¹ Heart Institute (Instituto do Coração-InCor), Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil. Electronic address: debbelfort@gmail.com.
² Heart Institute (Instituto do Coração-InCor), Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil.
³ Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
⁴ Hospital Sirio-Libanes, Sao Paulo, Brazil.

No abstract available

Keywords: beta-blocker; carvedilol; drug withdrawal; heart failure with improved ejection fraction; recovered ejection fraction.