Abstract
We tested cross-neutralization against highly pathogenic avian influenza A(H5N1) virus in adults vaccinated with 2021-2023 seasonal quadrivalent influenza vaccine in the United Kingdom. Seasonal quadrivalent influenza vaccines are unlikely to protect vulnerable persons against severe H5N1 disease during widespread transmission. Enhanced measures are needed to protect vulnerable people from H5N1 virus infection.
Keywords:
United Kingdom; highly pathogenic avian influenza; influenza; influenza A; neutralization; quadrivalent influenza vaccine; viruses; zoonoses; zoonotic transmission.
MeSH terms
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Adult
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Antibodies, Neutralizing* / blood
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Antibodies, Neutralizing* / immunology
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Antibodies, Viral / blood
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Antibodies, Viral / immunology
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Female
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Humans
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Influenza A Virus, H5N1 Subtype* / immunology
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Influenza Vaccines* / administration & dosage
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Influenza Vaccines* / immunology
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Influenza, Human* / epidemiology
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Influenza, Human* / immunology
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Influenza, Human* / prevention & control
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Influenza, Human* / virology
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Male
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Middle Aged
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Neutralization Tests
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Seasons
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United Kingdom / epidemiology
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Young Adult
Substances
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Influenza Vaccines
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Antibodies, Neutralizing
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Antibodies, Viral