Background: How weekend catch-up sleep (WCS) influences chronic kidney disease (CKD) risk is unknown. We investigated the association between WCS and CKD prevalence in adults.
Methods: In the National Health and Nutrition Examination Survey (NHANES, 2017-2020) participants (n = 4,961; age ≥ 40 years), we assessed the relationships of WCS (>1 hour increased sleep duration on weekends) with CKD and albuminuria prevalence via multivariate logistic regression analysis adjusted for potential confounders.
Results: WCS participants exhibited notably both lower CKD and albuminuria prevalence than non-WCS participants did, even after confounding variable adjustment (adjusted odds ratio [OR], 0.67; 95% confidence interval [CI], 0.46-0.96 and OR, 0.69; 95% CI, 0.49-0.97, respectively). Specifically, 1 to 2 hours of WCS were associated with decreased CKD (OR, 0.58; 95% CI, 0.38-0.89; p = 0.02). Furthermore, 1 to 2 hours of WCS were also significantly associated with lower albuminuria (OR, 0.11; 95% CI, 0.05-0.22; p < 0.001) among individuals sleeping <6 hours on weekdays.
Conclusion: WCS, particularly 1 to 2 hours, was significantly associated with a lower CKD prevalence in the middle-aged and older population, and albuminuria risk among those with restricted weekday sleep. These findings suggest that maintaining adequate sleep duration through WCS is linked to beneficial effects on kidney health. Longitudinal studies are needed to confirm these results.
Keywords: Albuminuria; Chronic kidney disease; Sleep duration; Weekend catch-up sleep.