Low rates of endothelial cell dysfunction and transplant-related mortality in 537 children receiving fludarabine-treosulfan conditioning for all transplant indications: A retrospective multicentre study on behalf of the UK Paediatric BMT group

Br J Haematol. 2025 Jun 1. doi: 10.1111/bjh.20184. Online ahead of print.

Thomas Altmann^{1

2}, Kanchan Rao³, Ramya Hanasoge-Nataraj⁴, Katharine Patrick⁵, Ben Carpenter⁶, Rachael Hough⁶, Anna-Maria Ewins⁷, Sanjay Tewari⁸, Oana Mirci-Danicar^{4

9}, Mary Slatter^{1

2}, Robert Wynn^{10

11}, Su Han Lum^{1

12}

¹ Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
² Paediatric Immunology, Great North Children's Hospital, Newcastle upon Tyne, UK.
³ Bone Marrow Transplantation, Level 4, CBL, Great Ormond Street Hospital, London, UK.
⁴ Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester, UK.
⁵ Department of Paediatric Haematology, Sheffield Children's Hospital, Sheffield, UK.
⁶ Adolescent Haematology, University College London Hospitals NHS Foundation Trust, London, UK.
⁷ Department of Haematology, Royal Hospital for Sick Children, Glasgow, UK.
⁸ Paediatric Haematology, King's College London School of Medicine, King's College Hospital, London, UK.
⁹ Bone Marrow Transplant Unit, Bristol Royal Children's Hospital, Bristol, UK.
¹⁰ Central Manchester University Hospital, Manchester, UK.
¹¹ Blood and Marrow Transplant, Manchester, UK.
¹² Department of Paediatric Haematopoietic Stem Cell Transplant, New Victoria Wing, Great North Children's Hospital, Newcastle Upon Tyne, UK.

No abstract available

Keywords: children; stem cell transplantation; treosulfan.