Objective: To understand the consultation for post-exposure prophylaxis(PEP) services and their related factors among college students who were at high risk for HIV infection in Hangzhou,and to provide a reference basis for formulating an intervention model for college students at high risk of HIV infection. Methods: A cross-sectional survey was conducted between November 2022, and March 2023, in 5 different types of schools in Hangzhou. The subjects should meet the inclusion criteria of age between 18 years and 24 years old self-reported having ever had sex in the past. The sample size was estimated at 864. An online survey was conducted among college students by questionnaire star of an online survey platform to collect their demographic information, sexual behavior characteristics, HIV test status, and consultation for PEP services. The HIV infection risk among participants was evaluated according to their sexual behavior. The consultation for PEP services and the related factors of college students who were at high risk for HIV infection were analyzed. Results: A total of 20 973 college students were surveyed, and 2 291 who have ever had sex were recruited in the study. The proportion assessed as being at high risk for HIV infection was 43.47% (996/2 291), and the proportion of consultation for PEP services was 9.24% (92/996). Multivariate logistic regression analysis showed that among college students who were at high risk for HIV infection, the positive related factors of consultation for PEP services included knowing about PEP services (aOR=17.49, 95%CI: 7.98-38.36) ,having HIV tests (aOR=3.92, 95%CI: 2.08-7.42) and access to condoms on campus (aOR=3.38, 95%CI: 2.02-5.65), and the negative related factor was homosexual orientation (aOR=0.24, 95%CI: 0.06-0.91). Conclusions: Among college students who were at high risk for HIV infection, the proportion of consultation for PEP services was at a lower level. It is necessary to strengthen further the health education of PEP services knowledge among college students, improve the PEP services system, and promote the utilization of PEP services to reduce new HIV infections among college students.
目的： 分析杭州市HIV感染高风险的大学生咨询HIV暴露后预防（PEP）用药服务情况及相关因素，为制定HIV感染高风险的大学生干预模式提供参考依据。 方法： 采用横断面研究设计，于2022年11月至2023年3月，选取杭州市5所高等院校的大学生为研究对象，纳入标准为自我报告（自报）发生过性行为的18~24岁在校大学生，样本量估计为864人。采用问卷星设计电子调查问卷，收集其社会人口学、性行为、HIV检测、咨询PEP用药服务等信息，根据其性行为情况评估HIV感染风险，分析HIV感染高风险的大学生咨询PEP用药服务情况及相关因素。 结果： 在参加问卷调查的大学生20 973人中，自报有性行为的比例为10.92%（2 291/20 973），被评估为HIV感染高风险者的比例为43.47%（996/2 291），咨询PEP用药服务的比例为9.24%（92/996）。多因素logistic回归分析结果显示，在HIV感染高风险的大学生中，咨询PEP用药服务的正相关因素包括知晓PEP用药服务（aOR=17.49，95%CI：7.98~38.36）、做过HIV检测（aOR=3.92，95%CI：2.08~7.42）和能够从校内获取到安全套（aOR=3.38，95%CI：2.02~5.65），负相关因素为性取向为同性恋者（aOR=0.24，95%CI：0.06~0.91）。 结论： 在杭州市HIV感染高风险的大学生中，咨询PEP用药服务的比例较低。为降低大学生的HIV感染风险，建议加强对大学生PEP用药服务知识的宣传教育，完善PEP用药服务体系，促进其PEP用药服务的利用。.