Three new ent-kaurene diterpenoid glucosides-Inunicosides L (1), M (2), and N (3)-along with five known analogs (4-8) were isolated from Inula japonica Thunb. Their structures were characterised using 1D and 2D NMR, HRESIMS, and electronic circular dichroism analysis. All compounds were assessed for anti-inflammatory activity.
Keywords: Inula japonica Thunb.; NO production; anti-inflammatory activity; ent-kaurene diterpenoid glucosides; structural elucidation.