The annual increase in the incidence of Parkinson's disease (PD) underscores the critical need for effective detection methods and devices. Gait video features based on camera sensors, as a crucial biomarker for PD, are well-suited for detection and show promise for the development of portable devices. Consequently, we developed a single-step segmentation method based on Savitzky-Golay (SG) filtering and a sliding window peak selection function, along with a Cross-Attention Fusion with Mamba-2 and Self-Attention Network (CMSA-Net). Additionally, we introduced a loss function based on Maximum Mean Discrepancy (MMD) to further enhance the fusion process. We evaluated our method on a dual-view gait video dataset that we collected in collaboration with a hospital, comprising 304 healthy control (HC) samples and 84 PD samples, achieving an accuracy of 89.10% and an F1-score of 81.11%, thereby attaining the best detection performance compared with other methods. Based on these methodologies, we designed a simple and user-friendly portable PD detection device. The device is equipped with various operating modes-including single-view, dual-view, and prior information correction-which enable it to adapt to diverse environments, such as residential and elder care settings, thereby demonstrating strong practical applicability.
Keywords: Mamba-2; Parkinson’s disease; attention; camera sensor; video-based detection.