OsDNR1 as a key regulator of rice resistance to 4-hydroxyphenylpyruvate dioxygenase-inhibiting herbicides

Yang Li; Xitie Ling; Wenting Zhang; Dongshu Guo; Jinyan Wang; Zeyu Qiu; Yuanda Lv; Yuwen Yang; Qing Liu; Xiaodong Hou; Baolong Zhang

doi:10.1111/jipb.13962

OsDNR1 as a key regulator of rice resistance to 4-hydroxyphenylpyruvate dioxygenase-inhibiting herbicides

J Integr Plant Biol. 2025 Jun 27. doi: 10.1111/jipb.13962. Online ahead of print.

Authors

Yang Li^{1

2}, Xitie Ling^{2

3}, Wenting Zhang^{2

3}, Dongshu Guo^{2

3}, Jinyan Wang^{2

3}, Zeyu Qiu^{2

3}, Yuanda Lv^{2

3}, Yuwen Yang^{2

3}, Qing Liu^{2

3}, Xiaodong Hou^{2

3}, Baolong Zhang^{1

2

3}

Affiliations

¹ School of Tropical Agriculture and Forestry, Hainan University, Haikou, 570228, China.
² Provincial Key Laboratory of Agrobiology and Institute of Germplasm Resources and Biotechnology, Jiangsu Academy of Agricultural Sciences, Nanjing, 210014, China.
³ Zhongshan Biological Breeding Laboratory, Nanjing, 210014, China.

PMID: 40576052
DOI: 10.1111/jipb.13962

Abstract

DULL NITROGEN RESPONSE 1 (OsDNR1) is a key gene in rice resistance to herbicides that target 4-hydroxyphenylpyruvate dioxygenase, which are phytotoxic due to their effects on homogentisic acid levels. Knocking out OsDNR1 leads to hydroxyphenylpyruvic acid accumulation in rice plants, thereby increasing homogentisic acid levels and conferring herbicide resistance.

Abstract

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