Increasing Placebo Response Rates and the Threat to Clinical Trials: How Will We Identify Effective Treatments for Rheumatic Disorders?

Arthritis Rheumatol. 2025 Jun 30. doi: 10.1002/art.43303. Online ahead of print.

Matthew J Parkes^{1

2

3}, David T Felson⁴, Michael P LaValley⁵

¹ Centre for Biostatistics, Division of Population Health, Health Services Research & Primary Care, School of Health Sciences, University of Manchester, Manchester, UK.
² NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre (MAHSC)m, Manchester, UK.
³ NIHR HealthTech Research Centre in Emergency and Acute Care, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre (MAHSC), Manchester, UK.
⁴ Department of Rheumatology, Boston University Chobanian and Avedisian School of Medicine, Boston, MA.
⁵ Boston University School of Public Health, Boston, MA.

No abstract available

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