Effect and safety of immune checkpoint inhibitors in metastatic lung cancer: A retrospective study

Bioinformation. 2025 Mar 31;21(3):534-537. doi: 10.6026/973206300210534. eCollection 2025.

Abstract

Cancer is a major global public health issue. Immune checkpoint inhibitors are increasingly used for managing advanced malignancies. However, their effect is limited by immune-related adverse events. Hence, a retrospective, single-institutional study found a 60% clinical benefit ratio among 30 patients receiving Immune checkpoint inhibitors therapy. Nonetheless, a small sample size, patient heterogeneity and retrospective design require further validation for more conclusive results.

Keywords: Non-Small Cell Lung Cancer; efficacy; immunotherapy; nivolumab; real-life.