Age and body mass index are associated with type Ⅲ aortic arch in patients undergoing digital subtraction angiography

Huiyang Qu; Nan Zhang; Yuxuan Cheng; Shuang Du; Xiaodong Zhang; Mengying Chen; Jiaxin Fan; Qingling Yao; Shuyin Ma; Meijuan Zhang; Kaili Shi; Yizhou Huang; Meiling She; Ruitao Xie; Shuqin Zhan

doi:10.1016/j.clineuro.2025.109036

Age and body mass index are associated with type Ⅲ aortic arch in patients undergoing digital subtraction angiography

Clin Neurol Neurosurg. 2025 Jul 1:257:109036. doi: 10.1016/j.clineuro.2025.109036. Online ahead of print.

Authors

Affiliations

¹ Department of Neurology, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
² Department of Neurology, the Yulin North Hospital, Yulin, Shaanxi, China.
³ Department of Neurology, the Shangluo Central Hospital, Shangluo, Shaanxi, China.
⁴ Department of Neurology, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China. Electronic address: sqzhan@mail.xjtu.edu.cn.

PMID: 40616974
DOI: 10.1016/j.clineuro.2025.109036

Abstract

Background and purpose: Type Ⅲ aortic arch can increase the difficulty of interventional surgery in patients with cerebrovascular diseases. This study was performed to explore the factors associated with type Ⅲ aortic arch.

Materials and methods: This observational, multicenter, case-control study was performed in Shaanxi Province, China and involved 841 patients who underwent cerebral angiography at 3 stroke centers from April 2019 to August 2020. The data for women and men were analyzed separately. We analyzed the differences between type I or Ⅱ aortic arch and type Ⅲ aortic arch and sought to identify factors related to type Ⅲ aortic arch.

Results: Among men, compared with patients with type I or Ⅱ aortic arch, patients with type Ⅲ aortic arch were older (odds ratio, 1.03; 95 % confidence interval, 1.01-1.05; P = 0.007) and had a lower body mass index (odds ratio, 0.83; 95 % confidence interval, 0.76-0.89; P < 0.001). Among women, compared with patients with type I or Ⅱ aortic arch, patients with type Ⅲ aortic arch were older (65.0 versus 62.0 years; P = 0.001).

Conclusions: Our findings suggested that advanced age and a lower body mass index were independent predictors of type Ⅲ aortic arch in male patients undergoing cerebral angiography. In female patients, only advanced age was an independent predictor of type Ⅲ aortic arch.

Keywords: Aortic arch; Aortic arch morphology; Body mass index; Type Ⅲ aortic arch.