Clinical Outcomes of Selective Laser Trabeculoplasty in Military Pilots with Open-Angle Glaucoma: Implications for Intraocular Pressure Control and Aeromedical Certification

Photodiagnosis Photodyn Ther. 2025 Jul 10:104717. doi: 10.1016/j.pdpdt.2025.104717. Online ahead of print.

Abstract

Objective: The aim of this study is to evaluate the clinical efficacy and safety of selective laser trabeculoplasty (SLT) in individuals diagnosed with open-angle glaucoma within the military pilot population and to examine its impact on intraocular pressure (IOP) regulation and aeromedical certification status.

Methods: A retrospective analysis was conducted using clinical data from four military pilots (eight eyes) who underwent SLT at the Ophthalmology Department of the Air Force Specialized Medical Center between January 2013 and January 2025. Outcomes assessed included 24-hour IOP fluctuations before and after SLT, changes in pharmacological management, and medical certification results.

Results: A statistically significant reduction in mean IOP was observed in six eyes following SLT (p < 0.05), with accompanying decreases in both the 24-hour peak IOP and IOP fluctuation range (p < 0.05). Among the four cases, two individuals demonstrated a reduction or cessation in the use of IOP-lowering medications. All individuals exhibited stable ocular conditions post-treatment and retained or regained their flight qualification status.

Conclusion: Based upon the 4 cases of primary open-angle glaucoma investigated, SLT demonstrated favourable safety and efficacy in lowering IOP and reducing medication dependencey in this cohort. Among military pilots with open-angle glaucoma or ocular hypertension, SLT may be regarded as a viable therapeutic option that supports the maintenance of flight readiness and aeromedical certification.

Keywords: glaucoma; intraocular pressure; medical certification; military pilots; ocular hypertension; selective laser trabeculoplasty.