Comparative pathology of mammary tumorigenesis in transgenic mice

R D Cardiff; R J Munn

doi:10.1016/0304-3835(94)03672-6

Comparative pathology of mammary tumorigenesis in transgenic mice

Cancer Lett. 1995 Mar 23;90(1):13-9. doi: 10.1016/0304-3835(94)03672-6.

Authors

R D Cardiff¹, R J Munn

Affiliation

¹ Department of Pathology, School of Medicine, University of California, Davis 95616, USA.

PMID: 7720037
DOI: 10.1016/0304-3835(94)03672-6

Abstract

Mammary tumors arise in transgenic mice bearing growth factors, proto-oncogenes, oncogenes and tumor suppressor genes. The tumors arise from hyperplasias. The tumor natural history and histogenesis are oncogene specific. Interactions between oncogenes may impede or accelerate tumorigenesis.

Publication types

Comparative Study

MeSH terms

Animals
Genes, Tumor Suppressor*
Hyperplasia
Mammary Neoplasms, Experimental / classification
Mammary Neoplasms, Experimental / genetics*
Mammary Neoplasms, Experimental / pathology*
Mice
Mice, Transgenic
Oncogenes*