Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene

Adv Prostaglandin Thromboxane Leukot Res. 1995:23:145-50.
No abstract available

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Arachidonate 5-Lipoxygenase / genetics*
  • Arachidonic Acid / pharmacology
  • Bone Marrow Cells
  • Carrageenan
  • Dinoprostone / analysis
  • Female
  • Inflammation / physiopathology
  • Leukotriene C4 / analysis
  • Leukotrienes / deficiency*
  • Macrophages / physiology
  • Male
  • Mast Cells / cytology
  • Mast Cells / physiology
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred Strains
  • Mice, Mutant Strains
  • Phagocytosis
  • Phenotype
  • Platelet Activating Factor / pharmacology
  • Spleen / physiology
  • Tetradecanoylphorbol Acetate / pharmacology

Substances

  • Leukotrienes
  • Platelet Activating Factor
  • Arachidonic Acid
  • Leukotriene C4
  • Carrageenan
  • Arachidonate 5-Lipoxygenase
  • Dinoprostone
  • Tetradecanoylphorbol Acetate