Cytokines in alcoholic liver cirrhosis

O Le Moine; A Marchant; M Goldman; E Dupont; J Devière

Cytokines in alcoholic liver cirrhosis

Acta Gastroenterol Belg. 1994 May-Aug;57(3-4):245-54.

Authors

O Le Moine¹, A Marchant, M Goldman, E Dupont, J Devière

Affiliation

¹ Department of Gastroenterology and Immunology, ULB, Hôpital Erasme, Bruxelles.

PMID: 7810273

Abstract

Interest for cytokines involvement in experimental and human liver injury has considerably increased over recent years. The present paper reviews the current knowledge in the field of alcoholic cirrhosis. The role of interleukin-1, tumor necrosis factor, interleukin-6, interleukin-8 and interleukin-10 are discussed together with their possible diagnostic and prognostic significance. Prospects for future investigations such as immunotherapy are underlined.

Publication types

Review

MeSH terms

Bacterial Infections / blood
Bacterial Infections / complications
Biomarkers
Cytokines / biosynthesis*
Cytokines / pharmacology
Humans
Immunoglobulin A / metabolism
Interleukin-1 / biosynthesis
Interleukin-10 / biosynthesis
Interleukin-6 / biosynthesis
Interleukin-8 / biosynthesis
Liver Cirrhosis, Alcoholic / complications
Liver Cirrhosis, Alcoholic / immunology
Liver Cirrhosis, Alcoholic / metabolism*
Tumor Necrosis Factor-alpha / biosynthesis

Substances

Biomarkers
Cytokines
Immunoglobulin A
Interleukin-1
Interleukin-6
Interleukin-8
Tumor Necrosis Factor-alpha
Interleukin-10