Four case-studies illustrate the therapeutic work with families of psychotic patients comprehensively treated in our day clinic. Individualization of goals and principles of such therapeutic work was pointed out in relation to families' needs as well as to the possibility of establishing their cooperation in the treatment proposed. Processes of mutual changes in patients' and families' attitudes toward themselves and to the illness are described. Attention was paid to many difficulties associated with leading of this kind of therapy as well as to a variety of signs of its positive influence on patients' and their families' functioning. This influence became noticeable sometimes only from a long-term perspective.