Thymidylate synthetase: fluorine-19 nmr characterization of the active site peptide covalently bound to 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate

Biochem Biophys Res Commun. 1976 Sep 20;72(2):404-10. doi: 10.1016/s0006-291x(76)80057-5.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Binding Sites
  • Fluorine
  • Fluorodeoxyuridylate* / metabolism
  • Fourier Analysis
  • Lacticaseibacillus casei / enzymology
  • Magnetic Resonance Spectroscopy
  • Methyltransferases* / metabolism
  • Protein Binding
  • Protein Conformation
  • Tetrahydrofolates* / metabolism
  • Thymidylate Synthase* / metabolism
  • Uracil Nucleotides* / metabolism

Substances

  • Tetrahydrofolates
  • Uracil Nucleotides
  • 5,10-methylenetetrahydrofolic acid
  • Fluorodeoxyuridylate
  • Fluorine
  • Methyltransferases
  • Thymidylate Synthase